Recombinant Human FGF-4 Synonyms:Fibroblast Growth Factor-4, HST-1, transforming protein KS3, HBGF-4
詳細介紹
Description:
FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106units/mg.
Cross Reactivity:
Mouse, Rat, Human, N/A, Pig
Research Interests:
Angiogenesis/ Cardiovascular
FGF Superfamily
Proliferation
Stem Cells & Differentiation
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.
